A person who exhibits chimerism has cells from two or more different genetic sources in their body. Fraternal twin embryos fusing in the womb or organ or bone marrow transplantation are two examples of how this can occur. As a result, a chimaera may have distinct DNA in various bodily areas, making them a combination of two or more genetic sets.continue reading
Chimerism can occur through different mechanisms, and the causes of chimerism are primarily related to genetic mixing during early development or through medical interventions. Here are some common causes:
Natural chimerism: It can occur when fraternal twin embryos fuse in the womb, leading to the exchange of cells and genetic material between the embryos.
Organ or tissue transplantation: Chimerism can be induced when a person receives a transplanted organ or bone marrow from a donor. The transplanted cells may coexist with the recipient’s cells in the body, leading to a mixed genetic makeup.
Blood transfusions: In some cases, blood transfusions can result in the temporary presence of the donor’s blood cells in the recipient’s bloodstream, causing a transient form of chimerism.
Fetal-maternal microchimerism: During pregnancy, small numbers of fetal cells can pass into the mother’s body and vice versa. This phenomenon is known as fetal-maternal microchimerism.
Artificial chimerism: In rare cases, chimerism can be artificially created in the laboratory for research purposes.
It’s essential to note that chimerism is a naturally occurring phenomenon and not a medical condition that requires treatment. It